do up

I.
vb
1.
to inject or inhale (a drug). An embel-lishment of do in the sense of 'take (drugs)' common among illicit drug users since the early 1970s.
2.
See done up
II.
do (someone) up
vb
British
to discomfit, defeat, confound
► 'Those long-haul flights really do you up.' (Recorded, female traveller, London, 2003)

Contemporary slang . 2014.

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